Word: sulfa
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...modern version of Ophelia's plaint could still be sung by mad-eyed U.S. pharmacists. But not much longer. For the supply of many herb-grown medicines is dwindling, and some prices have shot up as much as 200%. Synthetic drugs, such as arsenic compounds for syphilis, or sulfa drugs for infections, are still plentiful, but of the 300 plants commonly used in medicine, only 31 are grown commercially in the U.S. and those in small quantities. Many precious herbs could be grown in the U.S. and in South America, but their successful culture would take years of careful...
Though far from being a drug on the market, the number of sulfa drugs has increased so rapidly during the past two years that not even doctors can keep their uses straight. In the July issue of California and Western Medicine last week, Drs. Lowell Addison Rantz and Windsor Cooper Cutting gave a brief review of the whole sulfonamide family, with the diseases on which each drug works best. The ideal sulfa drug, they said, is still to seek. Requirements: it must be as strong as possible, without poisoning the patient...
...present." It is a powerful weapon against pneumonia, staphylococcic infections and a great range of streptococcic infections. Resultant anemia and cyanosis are "less marked" than with the use of sulfanilamide. But sulfathiazole has other drawbacks: 1) it causes fever, skin rash, inflammation of the eyes more severely than other sulfa drugs; 2) it must be used for a relatively longer period of time, thus increasing danger of complications...
Sulfadiazine seems to be "rather non-toxic." It is "very promising at the moment and may prove to be the next step in the sulfonamide ladder." (Last week Perrin Long of Johns Hopkins, top-flight sulfa specialist, announced that this drug will be on the market by early fall. Said he: "I have good reason to believe it will supplant all sulfa drugs now being used...
Yellow Marrow. Often large doses of sulfa drugs drain the body's reserves of white blood cells. (So does arsphenamine, the syphilis specific, and certain sedatives and painkillers.) A deficiency of white blood cells may also be caused by disease of the bone marrow, where most of them are produced. This form of blood disease, known as agranulocytosis or leukopenia, leaves the body at the mercy of any bacteria which may enter the bloodstream. For the white cells, which move about like amebae, are the body's shock troops; they gobble up invading bacteria, produce antidotes which neutralize...