Word: summing
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Further, the tremendous sum that it costs to get a drug approved severely constrains the number of drugs companies are willing to develop. If a pharmaceutical company cannot expect to make back their costs—which could reach over $1 billion—in sales from a drug, it will not even go to the trouble of submitting the drug for FDA approval. This limits the options available to those with rare diseases, because the FDA creates a huge disincentive to make drugs that will only help a “niche” market. That explains...
...comparison, the Xbox 360 costs $400 for a basic version and $500 for one with a hard drive; the Nintendo Wii console will debut two days after PS3 for about half the price.) Throw in a few PS3 games, at $60 a pop, and you're out $900-a sum that may scare off consumers. And PS3 already frightens stock analysts. "We do not believe the machine provides incentives for buyers to buy a new machine ... except some game maniacs," Merrill Lynch analyst Hitoshi Kuriyama wrote in a recent report. Sony has already cut the price of the basic model...
...That sum will only make a dent in the production’s total operating expenses. “We’re always right on the edge of being over budget,” says Keller...
...kidnapping ring has demanded a $250,000 ransom from the family of the U.S. soldier abducted in Iraq, a suspiciously low sum that his family worries could be a sign that he is no longer alive...
...scene straight out of a Hong Kong gangster flick. On a November morning in 2002, local property tycoon Harry (Cigar) Lam was enjoying breakfast in his usual spot at Luk Yu Tea House, a Hong Kong institution famed for its tasty dim sum and indifferent service. At about 9 a.m., a nearby diner paid for his meal, walked up to Lam's table and killed him with a gunshot to the head...