Word: sweeney
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Corgan wasted no time in turning to new endeavors, however. After playing guitar with British band New Order for a summer, he created Zwan, a new group with Chamberlain, guitarist Mark Sweeney, guitarist and bassist David Pajo and, later in its run, bassist Paz Lenchantin...
...affair, both plots straight from Dawson's Creek Season 1. But its characters are much more believable--Dino, Ben and Jonathan aren't miniature adults, they're kids. When Dino finds his mom cheating, he's not just angry; he's scared, above all for his dad (D.B. Sweeney), a good-hearted sad sack who hates his pencil-pushing job. Fox's The O.C. transcended its soap roots with good writing and strong characters, including the adults; life isn't nearly as good yet, but it deserves a second date...
...Many were thrilled. More than 100 people immediately joined him at Holy Cross. Others were perplexed or heartbroken. "We're traditional people," says St. Alban's charter member Sue Henson. "We're not for Gene Robinson's election, but differences can only be worked out if you stay." Marian Sweeney is peeved that Beach gave so little notice. "You don't make a move like that in a week," she alleges. "He had been accepted by the Bishop of Bolivia before he announced he was leaving. He kept us in a holding pattern, saying Be patient and pray. And then...
...then, to using IGF-1 safely and effectively in muscular-dystrophy patients lies in getting enough of the hormone directly to the muscle. So Sweeney's group is perfecting a version of gene therapy, the most efficient way to dump a large amount of genetic material into a tissue as extensive as muscle (about 40% of body weight comes from muscle). He packs the IGF-1 gene into a harmless cold virus and injects the entire package directly into muscle. Once the IGF-1 gene inserts itself into the genome of the muscle cell, it begins to churn...
Boosting IGF-1 levels is only half the story. Sweeney is also trying to tip the balance by shutting down myostatin, a compound that inhibits IGF-1 activity in the muscle. The pharmaceutical maker Wyeth Ayerst is testing a myostatin blocker in early trials of healthy humans, and hopes that it may become a new treatment option for those with muscular dystrophy or for the elderly who have become frail from the normal muscle wasting that occurs with aging...