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...1960s, a second class of antidepressants emerged. By tinkering with the chemical structure of antihistamines, a Swiss psychiatrist, Ronald Kuhn, created a drug called imipramine, first of the so-called tricyclic antidepressants. At the time no one had any idea why these medicines worked. Researchers have since learned that they keep excess serotonin and other neurotransmitters from being reabsorbed into the nerve cells they originally came from: same extended neurotransmitter bath as the MAO inhibitors, different mechanism...

Author: /time Magazine | Title: THE MOOD MOLECULE | 9/29/1997 | See Source »

...first business before he had fully mastered a bicycle. The venture was a variation on a classic model: converting backyard lemons to lemonade. Next the brothers started Case Enterprises, which peddled everything from seeds to watches. Case Enterprises stumbled--"I can't understand why no one wanted to buy Swiss watches from a 12-year-old and an 11-year-old," Dan jokes--but it gave the boys a feel for the joys of capitalism. "From the beginning," Steve says, "it was clear I'd be an entrepreneur...

Author: /time Magazine | Title: HOW AOL LOST THE BATTLES BUT WON THE WAR | 9/22/1997 | See Source »

...affinities with his mother, William has recently begun to shoulder royal duties. Last January, the increasingly independent William chose to forgo a Swiss ski vacation with his father and brother and stay at Sandringham with the Queen, Prince Philip and a host of junior royals and friends, including his pal and cousin Peter Phillips, son of Princess Anne. He apparently has a close relationship with his grandmother, whom he regularly visits at Windsor for Sunday-afternoon tea and chats about his future role. "Relationships with grandchildren are always easier than those with your own children," says someone who knows...

Author: /time Magazine | Title: THE MEN WHO WOULD BE KING | 9/15/1997 | See Source »

...perspective owes much to the work of Swiss archaeologist Charles Bonnet, who has spent the past 24 years excavating Kerma, the seat of Africa's greatest empire (outside Egypt) between 2500 B.C. and 1500 B.C. Bonnet acknowledges that he went to Sudan initially to find Egyptian civilization. "But step by step," he confesses, "I came to understand that the Nubian civilizations are really extraordinary. There might be Egyptian influences, but there is a Nubian originality and a Nubian identity...

Author: /time Magazine | Title: THE NILE'S OTHER KINGDOM | 9/15/1997 | See Source »

...looking into Switzerland's role during World War II. Why are questions about Volcker's Nestle position being raised now? Perhaps because in a recent letter to a federal judge who must decide whether or not to dismiss a multibillion-dollar class action brought by Holocaust victims against the Swiss banks, Volcker argued that their suit would have a potentially "crippling" impact on his investigation. Other members of the eminent-persons group immediately dissociated themselves from Volcker's letter, and made it clear that it was his concern, not theirs. Lawyers for the victims are questioning Volcker's business ties...

Author: /time Magazine | Title: SWISS FINANCE | 8/25/1997 | See Source »

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