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Aside from vaccination, the only prophylactic against any strain of Asian flu is amantadine, a drug marketed by Du Pont as Symmetrel. It is given to the elderly and infirm after one member of the household has come down with flu but before they develop it themselves. It is ineffective after illness has begun, and many physicians question whether its safety for those of all ages and sexes has been sufficiently proved. No matter how widely the new vaccine is distributed or how fast it is used, this is going to be the winter of the flu. And Hong Kong...

Author: /time Magazine | Title: Infectious Diseases: A2-Hong Kong-68, or Whatever | 12/13/1968 | See Source »

...pairs of shoes with Du Pont's three-year-old synthetic Corfam, which is supposed to look, feel and "breathe" like natural leather. Early this year, after twelve years and $8,000,000 in research, the company invaded the rich pharmaceutical field by marketing an antiflu drug named Symmetrel, which can be taken orally as either a pill or syrup. Only two weeks ago, the company introduced a recording tape aimed at the multimillion-dollar computer, television-broadcast and instrument markets. Called Crolyn, the patented tape uses chromium dioxide as its magnetic medium in place of conventional iron oxide...

Author: /time Magazine | Title: Chemicals: Painful Adjustment at Du Pont | 6/30/1967 | See Source »

...drug, Du Font's amantadine hydrochloride, is virtually the only medicine effective in preventing viral infections. Trade-named Symmetrel, it has been tested on more than 3,000 human subjects, and has shown remarkable effectiveness in protecting against Asian-A influenza. For an adult the effective dose of amantadine is 200 mg. a day, a tiny fraction of an ounce...

Author: /time Magazine | Title: Drugs: THE SAFETY OF SYMMETREL | 12/2/1966 | See Source »

Testing Prisoners. Like other explorers, Du Pont's chemists often discover not what they had set out to find but something far more intriguing. One notable case is the company's new anti-virus drug, Symmetrel, which derives from a compound of organic chemicals that has a uniquely diamond-shaped molecular structure and is called adamantane. First formulated by a pair of Yugoslav scientists in 1941, adaman-tane had long been a laboratory curiosity around the world-because of its unusual structure-when Du Pont asked its men to search out uses...

Author: /time Magazine | Title: Corporations: The Master Technicians | 11/27/1964 | See Source »

...never before tried. Copeland, for one, has special reason to be pleased: 20 years ago he proposed in writing that Du Pont turn its enormous research potential to the drug business. "The pharmaceutical companies have been queuing up at our door seeking rights to manufacture or sell Symmetrel," says he, "but we're going to market it ourselves...

Author: /time Magazine | Title: Corporations: The Master Technicians | 11/27/1964 | See Source »

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