Word: syntex
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...most spectacular performance last week occurred on the American Stock Exchange. After officers of Syntex, a supplier of basic material for oral contraceptive pills, reported that third-quarter earnings had more than trebled (to $5,900,000), the stock soared 22¾ points to 175¾-the biggest single-day advance in the recorded history of the American Exchange...
...Norlestrin (Detroit's Parke, Davis & Co.), a new, small-dose tablet. >Norinyl (Syntex Laboratories, Inc.), another new, small-dose pill...
...pill for five days. Its proponents claim that it comes closer to the natural physiological hormone cycle. Mead, Johnson & Co. already has an application before FDA asking approval of sequential-therapy pills compounded of ingredients bought from British Drug Houses, Ltd. And Indianapolis' Eli Lilly & Co., working with Syntex, is on the same tack. Michigan's Upjohn Co. is preparing a pill it calls Provest, and Pennsylvania's Wyeth Laboratories are testing still another...
...Code Words. If all this works out (there may be unforeseen difficulties), it is good news for those patients who are helped by cortisone. Perhaps even more promising is another aspect of the Syntex accomplishment. The steroid hormones are, in effect, "code words" which help to control the cells of the body. They are all very similar, built around the same nucleus, but the slightest difference (such as the shift of an oxygen atom from one carbon atom to another) changes their effect. Medical researchers would like to try hundreds of steroids to see what each can do to make...
...Syntex process produces, along the line, whole classes of promising steroid compounds. Some of them have been found in adrenal glands, but in quantities too small for practical experimenting. Now, says Syntex, these "cortisone precursors" can be made in any amount desired. Some of them may prove more potent biologically than cortisone itself...