Word: synuclein
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...first place to look for causes and treatments of Parkinsons disease is in the brains of patients themselves. As the illness worsens, brain tissue becomes clogged with a protein muck that includes a substance called alpha-synuclein. No one knows exactly what alpha-synuclein does, but its believed to play a role in the smooth transmission of nerve signals. When the substance clumps, it cant do the work it was designed to do, leading to neuron damage, loss of the neurotransmitter dopamine, and eventually to the familiar shakiness of such well-known Parkinson...