Word: systemic
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Dates: during 2010-2019
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...even WALL-E could clean up. The desaturated color scheme makes the whole world look as if it were left outside to die, and it was. Marauding punks prey on solitary travelers for water, food and clothing. With all industrial and agricultural sectors in shambles, the fear-market system applies: survival of the meanest. Or, in Eli's case, the purest. He's a good man with a Good Book - a rare extant copy of the Bible, whose possession he will defend with his life. (See the top 10 movies...
That may be true, but Ho, who has been working to develop an HIV vaccine of his own, now believes that a traditional shot, one that relies on snippets of a virus to both awaken and prod the immune system to churn out antibodies, may not be the best way to fight HIV. Rather than expecting the body to do all the work of first recognizing then mounting an attack against the virus, why not just present the body with a ready-made arsenal of antibodies that can home in on HIV? It's the immunological equivalent of a frozen...
...showed how HIV therapies would be most effective in the days and weeks immediately after HIV infected a new host. That understanding came from their breakthrough finding that rather than sitting latent for years after infection, as many experts believed at the time, HIV was actively challenging the immune system from Day One. Soon after that revelation, ADARC scientists were the first to add to existing data on how HIV worked by identifying a second, key receptor that the virus uses to invade cells...
...Vaccine Research Center at the National Institutes of Health (NIH). "It is constantly changing its genetic makeup through mutations. It's also a moving target because the proteins of the virus surface are actually moving themselves - they are conformationally flexible. The net result is that the immune system never gets a really good look at them...
...than just another member of the growing arsenal of ARV cocktails. Each of the ARVs focuses on thwarting just one of several different steps in HIV's infection process. Ibalizumab works at the critical juncture where the virus meets a healthy CD4 cell - a critical component of the immune system - essentially interposing itself between the two and preventing infection. If ibalizumab was so good at tamping down HIV in AIDS patients who were already infected, then maybe it could be tweaked to prevent AIDS in the first place. In other words, maybe it could become a vaccine - just a whole...