Word: tamiflu
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Dates: during 2000-2009
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...handle on how infectious a new influenza like H1N1 might be, how it spreads, and how quickly. That helps them know how much vaccine might be needed, how to distribute it, and when to expect a surge in demand for flu treatments, including antiviral drugs such as Tamiflu and Relenza. It can also help predict when hospitals might become overwhelmed by flu cases, and prepare them to patch up already strained health care resources...
Back to Normal Meanwhile, things have calmed down at Camp Modin. No child was hospitalized, even though about 1 in 5 of the campers and staff came down with the illness. Quarantined campers were carefully screened for any rise in body temperature, and Tamiflu was broadly administered, despite federal recommendations. The pandemic was integrated into normal camp life - just another reality like bug bites and sunburn. "The kids made light of it. It was just the flu," says Howie Salzberg, the camp's director. To help pass the time, quarantined kids were given access to television, DVDs and video games...
...team is also on the lookout for changes in the virus that might make it resistant to the antiviral drug Tamiflu, which has been shown to reduce the severity of the disease caused by many flu viruses. Tamiflu works by inhibiting the neuraminidase enzyme (that's the N in H1N1) and preventing it from doing its job of helping the virus replicate once inside a human cell. But certain amino-acid changes in the neuraminidase can render Tamiflu ineffective. This usually happens over time following extensive prescribing of the drug, but it can also occur spontaneously. In the winter...
...Managing the public's need for reliable information may prove as big a challenge as injecting the vaccine into people's arms. For instance, antivirals like Tamiflu are recommended in some cases for family members of those already sick with flu but not for large populations, like schools, that may have flu circulating in their midst. (Officials worry that widespread prophylactic use of antivirals could deplete stockpiles for people who really need them and create more deadly flu strains in the long run.) Officials must also explain that the seasonal-flu vaccine, which is specifically recommended for more than half...
...Back to Normal in the Northeast Meanwhile, things have calmed down at Camp Modin. No child was hospitalized, even though about 1 in 5 of the campers and staffers came down with the illness. Quarantined campers were carefully screened for any rise in body temperature, and Tamiflu was broadly administered, despite federal recommendations. The pandemic was integrated into normal camp life, just another reality like bug bites and sunburn. "The kids made light of it. It was just the flu," says Howie Salzberg, the camp's director. To help pass the time, quarantined kids were given access to television, DVDs...