Word: tamoxifen
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Dates: during 2000-2009
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...back then, when she was 32, a first-grade teacher with a 6-month-old and a 3-year-old and a disease that came out of nowhere. The doctors' advice was clear and aggressive: a lumpectomy, followed by six months of chemotherapy, then radiation, then five years of tamoxifen. Her ovaries came out because the tumors were estrogen-positive. And the minute she was able, she and her husband Dave and their girls began reaching out and fighting back...
...magazine [Oct. 15]. Breast cancer is indeed becoming a global concern and strikes women regardless of age or socioeconomic level. My fiancé, who is 32, is one of the survivors. She had surgery, received chemotherapy, went bald and took medicines mentioned in your report such as tamoxifen and Herceptin. She is currently healthy and living a better life than before. Having a strong will to survive means you are on your way to being cured; we leave the rest to prayers and medicine. Alexander Abimanyu, jakarta...
...struck by a type that is partly stimulated by exposure to estrogen. This is one reason the disease usually hits in middle age, after 25 or so years of the monthly hormonal surges associated with ovulation and menstruation. Since the cancer relies on estrogen to grow, drugs like tamoxifen and Herceptin, which block hormone receptors on malignant cells, can help starve the disease...
...greater likelihood of ER-negative breast cancer in Africans and Asians means that such drugs as the estrogen blockers are not on the menu of pharmaceutical options. That rules out one of the cheapest and most available breast-cancer drugs in Africa: a $150-a-dose generic version of tamoxifen (and even that would be far too expensive for many women). Traditional chemotherapy may cost $20,000 or more. Merely determining which type of cancer a woman has may require genetic testing, which can add an additional $3,000 to the bill...
...expensive) tests for different disorders. Women who carry a gene variant known to increase breast cancer risk, for example, would be able to begin mammograms earlier in life. Second, it would allow physicians to personalize medical treatments. In a few cases, this is already possible. The breast cancer drug Tamoxifen is much more effective in individuals who produce a certain protein that digests drugs in a certain way. Treatments based on the DNA you carry, known as “personalized medicine,” offer a range of benefits over current treatments: more precise doses of potentially toxic drugs...