Word: targetedly
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...Astex calls its drug discovery method "fragment-based,'' because rather than throwing an entire proposed drug molecule at the target protein, they throw just pieces at a time. Jhoti claims this yields a much higher success rate than trying out whole molecules, an approach favored by large drug companies like the one he left in 1999, Glaxo Wellcome...
...Another disease-fighting Pioneer is Jennie Mather of Raven Biotechnologies in South San Francisco. Like Jhoti, Mather is out to fight cancer, but her approach is radically different. She postulated that what really counts in a target protein - that is, a protein that causes a disease and that a drug would aim to disable - is the protein's surface. Since a body's natural antibodies never enter a diseased cell but do their work entirely on the cell's exterior, she reasoned, drugs should work the same way. Such thinking was heresy to her former employer Genentech, which analyzes...
However in the spirit of being over-serious—in a quintessentially Harvard way—Dartboard thinks it necessary to point out that the Commission is missing an easy target: the promises and vows made by the candidates in their platforms...
Hungry students must place their orders online. The service does not require a minimum order. It charges a $1.50 delivery fee for all orders under $7.50 and a 20 percent fee for more expensive ones, according to the website. Crimsonfood.com boasts a delivery target between 15 and 40 minutes after the order is placed, although they don’t guarantee...
...once the tax code is reformed, once California gets its fair share from Washington, Arnold could direct the klieg lights where they really belong—on preparing California for the future, and abolishing confusing voter initiatives that mandate irresponsible spending increases and guarantee fiscal insanity. And he could target investments in classrooms and mass transit, fix a broken workers’ compensation system, and help attract back the jobs that are fleeing for less expensive states. But he cannot be The People’s Governor until he stops just acting to fix the people’s government...