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...have to be given in larger doses to some patients or that some prostate cancers may mutate to the point where antiandrogen drugs are simply ineffective. "There could be changes that are preventing the drug from binding," he says. "It's a bit like trying to hit a moving target." But for now, MDV3100 offers some potential as better ammunition...

Author: /time Magazine | Title: Experimental Prostate-Cancer Drug Shows Promise | 4/8/2009 | See Source »

...question is, How can any of this be used to help autistic kids? Nobody recommends inducing fevers to kick-start the locus coeruleus, since that could lead to all manner of side effects and other ills. Instead, Mehler and Purpura believe the likeliest answer is in medications that target noradrenaline brain receptors. "First, we should look at the signaling pathways in the region of the brain involved," Purpura says. "Then we could look at treating the receptor sites with some kind of pharmacotherapy." For once, the step that's missing from a proposal is the one that involves shouting about...

Author: /time Magazine | Title: Why Fever Helps Autism: A New Theory | 4/7/2009 | See Source »

...unlike Harvard, Princeton plans to increase the fraction of the endowment it plans to spend—upping the spending rate from a projected 6.25 percent to 6.7 percent next year, which is higher than its usual target rate of 4 to 5.25 percent, according to Princeton University President Shirley M. Tilghman’s letter to the community on Monday. [SEE CORRECTION BELOW...

Author: By Bonnie J. Kavoussi, CRIMSON STAFF WRITER | Title: Princeton Forecasts Endowment Drop | 4/7/2009 | See Source »

...Keller's Per Se Bobby Flay's Bobby's Burger Palace Bugatti Veyron Fbg par Herms Prada Hyundai Genesis Valentino's Gstaad chalet Karl Lagerfeld's Vermont hideaway Nancy Gonzalez crocodile tote Tod's neoprene Pashmy Art Basel scoutingforart.com Alexander McQueen ready-to-wear McQ Alexander McQueen for Target DayJet's Eclipse500 air taxi service JetBlue's new terminal at J.F.K. International Airport Invitation-only Yellowstone Club resort 5-star Wynn Las Vegas offering $109/night specials Crme de la Mer Bliss's Best of Skintentions

Author: /time Magazine | Title: Luxury Goes Low-Key | 4/6/2009 | See Source »

...When I was originally hired as an events coordinator at the SOCH, this was one of several programming ideas that [David] had on the table,” O’Brien said. O’Brien added that in planning the event, coordinators didn’t specifically target students in the Visual and Environmental Studies department, who give their own end-of-semester screenings for class-based work. “It’s great that the VES students have a screening opportunity, but we wanted that platform to be available to everyone...

Author: By Edward-michael Dussom, CRIMSON STAFF WRITER | Title: SOCH Cinema Presents Film Fest | 4/6/2009 | See Source »

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