Word: targetting
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Dates: during 1990-1999
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...this massive show of communal support, it is embarrassing to note that some people attacked the drive as discriminating. One poster asked in large letters above a picture of Kuo, "Are you Asian?" underneath which was the response, "Then you could save my life." While the posters did target Asians, this one was done out of an understanding of the increased likelihood that Asians would have the bone marrow type that could save Kuo's life...
...days ago, Forbes magazine, the target of Turner's ire, released its annual list of the nation's 400 richest people. This year, the list included 170 billionaires, up from 135 in 1996. When the magazine started the list in 1982, there were just 13 billionaires...
...first glance, these stories seem completely unrelated--three profoundly different disorders treated with three different drugs. Yet all three medications have one crucial element in common: they target the brain chemical serotonin. Though serotonin has been known to researchers for nearly a half-century, only in recent years have neuroscientists begun to understand how important this one substance is to the functioning of the human psyche. Serotonin, or the lack of it, has been implicated not only in depression, uncontrollable appetite and obsessive-compulsive disorder but also in autism, bulimia, social phobias, premenstrual syndrome, anxiety and panic, migraines, schizophrenia...
...growing awareness of serotonin's central role in mood and emotion has been paralleled--and in some cases driven--by a boom in drugs that target serotonin more or less specifically. Among them are such popular antidepressants as Elavil, Prozac, Zoloft and the hot new herbal medication St. John's wort; powerful appetite suppressants including Redux and fenfluramine; and antipsychotics such as clozapine. Like every other drug, the ones that zero in on serotonin have side effects. Elavil makes people sleepy. Zoloft can trigger headache and nausea. Zoloft and Prozac may cause sexual dysfunction. All these symptoms are annoying...
...research into serotonin-boosting drugs is hardly slowing down. If anything, the discovery of a new set of side effects will spur researchers to hone their pharmacological handiwork even more, to create medicines that will not just fine-tune the way serotonin is used in the brain but might target specific serotonin receptors as well or act on only specific parts of the brain and nervous system...