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...resistant tuberculosis, a disease for which clinicians have never had a perfect therapy. The success of TB treatment depends on the destruction of active and dormant bacteria to prevent relapse - something that few existing antibiotics have been able to do. One way to kill a dormant cell is to target biochemical processes that continue even in latency - there aren't many of those. But myxopyronin works by interfering with the enzyme RNA polymerase, which controls gene transcription in cells and is necessary for cell survival, dormant...

Author: /time Magazine | Title: A New Class of Antibiotics Could Offer Hope Against TB | 10/17/2008 | See Source »

...Brussels summit did not formally decide anything on the climate change package: the 2020 target still remains a 20% cut in carbon emissions, a 20% boost in renewable energy, and a 20% rise in energy efficiency. But the mood has turned, and officials have backed away from pushing for details on how to achieve the cuts. E.U. governments and the European Parliament still have to agree them by December and turn them into law before next June's European elections...

Author: /time Magazine | Title: Is Europe Backsliding on Climate-Change Targets? | 10/16/2008 | See Source »

...Target Women If you're a female who enjoys basic cable (and according to marketers, all females do) but is driven crazy by the gender-specific ads, then salve the pain with Sarah Haskins' very funny recurring Target Women videos on Current.com You'll never see yogurt the same way again...

Author: /time Magazine | Title: Short List | 10/16/2008 | See Source »

...size of your co-payment or deductible). Such edgy marketing aims to attract Americans ages 19 to 29--nearly a third of these so-called young immortals forgo insurance because they think they either don't need it or can't afford it. Carriers are also starting to target another demographic: early retirees who are too young to be covered by Medicare...

Author: /time Magazine | Title: Insurance for $30 a Month | 10/16/2008 | See Source »

...Nicaraguan journalist and feminist leader Sofia Montenegro, a central target in the government's crackdown, predicts Ortega's "psychologically vulgar and manipulative campaign" will eventually boomerang on him. Montenegro says the personal nature of the attacks against her have been so crass that even the machista element of Nicaraguan society is rejecting what many view as a cowardly persecution of women. "Men think: that could be my sister, or my wife," she said...

Author: /time Magazine | Title: President Ortega vs. the Feminists | 10/16/2008 | See Source »

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