Word: tetraethylammonium
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Dates: during 1958-1958
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...operating table, the heart of the baby boy began fibrillating-quivering ineffectually. His surgeons quickly restored blood circulation by manual massage, but that solved nothing. Nearly an hour later, they tried something entirely new: a small (10-milligram) dose of tetraethylammonium chloride injected directly into the child's coronary artery system. Almost immediately the heart began beating regularly again...
...counter the magnesium, they finally tried tetraethylammonium chloride (TEA) on the strength of a report in a Swedish journal that TEA would remove magnesium-caused neuromuscular blocks in other parts of the body. Coupled with an electric shock, TEA promptly defibrillated 44 isolated dog hearts up to eight times each. The technique then saved the baby boy. In four other fibrillating human patients since treated in the same way, it has worked equally well. TEA may be the trick that wall allow considerably longer, cooler, safer heart operations than have been possible...
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