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...million, six-year trial, which involved more than 16,000 people in Thailand - the largest AIDS-vaccine trial ever conducted - found that an experimental vaccine was 31% effective in preventing HIV infection. The volunteer group in the study was representative of the general Thai adult population, including low-risk, heterosexual adults. Calling the results of the trial a "significant scientific advance," officials at the World Health Organization said the results reinvigorated the stalled quest for a vaccine against AIDS, which is estimated to kill some 2 million people globally each year. (See the top 10 medical breakthroughs...

Author: /time Magazine | Title: AIDS-Vaccine Trial Raises Hopes — and Questions | 9/25/2009 | See Source »

...scientists working on the trial, led in Thailand by the U.S. Army and the Thailand Ministry of Public Health, said they were baffled as to why the two seemingly ineffective vaccines appeared to work together. Another mystery was that the people who became infected with HIV developed roughly the same amount of virus in their blood whether they got the vaccine or the placebo. Typically a protective vaccine would lower a patient's so-called viral load, a criterion that physicians use as the main indicator of HIV infection. The outcome of the trial of RV144 suggests that scientists...

Author: /time Magazine | Title: AIDS-Vaccine Trial Raises Hopes — and Questions | 9/25/2009 | See Source »

...Program, says other unknowns remain about the vaccine, such as the duration of its effect, the potential need for additional boosters, its efficacy in higher-risk populations like intravenous drug users and, most crucially, whether it might work on other subtypes of the virus. "The vaccine was tested in Thailand against types of HIV that circulate in Thailand," Kim says, pointing out that a different strain of the virus causes high infection rates in Africa...

Author: /time Magazine | Title: AIDS-Vaccine Trial Raises Hopes — and Questions | 9/25/2009 | See Source »

...renewed threat of civil war in Burma isn't just an internal problem. The country's minorities are concentrated in its borderlands, and in recent weeks, as the junta has surged into rebel territory, tens of thousands of ethnic refugees have poured into Thailand and China...

Author: /time Magazine | Title: Inside Burma's War | 9/21/2009 | See Source »

...Shan State Army (also known as the Mongla army) and the Kokang Army. The junta's lightning strike on the Kokang capital Laogai, which is estimated to have caused some 200 civilian casualties, left the other alliance members ill-equipped to respond immediately. But exile groups in China and Thailand are reporting that the Wa - which, with some 25,000 foot soldiers and an arsenal of heavy artillery, is the strongest of the rebel armies - is providing support to the shreds of Kokang forces still fighting, as well as giving sanctuary to Kokang leader Peng Jiasheng. With the junta reinforcing...

Author: /time Magazine | Title: Inside Burma's War | 9/21/2009 | See Source »

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