Word: thymus
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Dates: during 1980-1989
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Using a high-energy X-ray beam, researchers at Stanford administered a total of 2,000 rads of radiation (less than half the dosage for Hodgkin's disease) to the lymph nodes of the neck, chest, abdomen, thymus gland and spleen. Patients were treated five days a week for five weeks. Within a month, all the patients started to improve; six months after the irradiation, disagreeable symptoms such as morning stiffness, pain and swelling within the joints were all significantly reduced...
Charles River critters have a distinguished history in the development and testing of vitamins, antibiotics, insulin, contraceptives and cancer drugs. Now the company has another product: the nude, athymic mouse, a hairless, pink-colored model bred without a thymus, the gland that helps the body develop immunity against outside infection. The first of these mice was an unexpected mutation, which was then bred to other mice in the Charles River labs. Now the company turns out more than 250,000 of these beasts annually. They are especially useful in cancer research because they will not reject a tumor transplant like...