Word: thyroglobulin
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...most clear-cut and comprehensible autoimmune diseases form a small, exceptional group. Thousands of the body's countless proteins circulate in the blood or are washed by it, but a few are "sequestered": the fluid in the eye's lens, sperm secreted in the testicles, and thyroglobulin (an iodine-containing protein), which usually stays locked in the thyroid gland. If lens fluid leaks into the bloodstream after injury, its proteins start the antibody factory working and the body seeks to destroy the lens proteins...
...lens. Thus injury to one eye may lead to blindness in both. Injury or inflammation of the testicles may force sperm proteins into the bloodstream, which then sets about destroying them-a process that causes temporary or even permanent sterility. If the thyroid gland is damaged or diseased, thyroglobulin may escape from its sequestered state, and a clearly defined form of thyroid disease results...
...scientific talk of "giant molecules." But molecules, infinitesimally tiny as they are by ordinary standards, vary greatly in size. Molecular weight of ethyl alcohol, for example, is 46 units; * of sodium chloride (salt), 58.5; of the hormone secretin, 5,000; of hemoglobin, about 68,000; of the thyroid substance thyroglobulin, about 700,000. Dr. Wendell Meredith Stanley and his associates at the Rockefeller Institute have crystallized the virus which causes mosaic disease in tobacco, found that it weighs 17,000,000 units (TIME, Nov.15). A rabbit wart virus was found to weigh 20,000,000 units, a horse encephalitis virus...
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