Word: thyroids
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Dates: during 1930-1939
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...living human body. . . . Organs removed from the human body, in the course of an operation or soon after death, could be revived in the Lindbergh pump, and made to function again when perfused with an artificial fluid. . . . When larger apparatus are built, entire human organs, such as pancreas, suprarenal, thyroid, and other glands . . . would manufacture in vitro the substances supplied today to patients by horses or rabbits...
...other applications of the method. For instance, diseased organs could be removed from the body and placed in the Lindbergh pump as patients are placed in a hospital. Then they could be treated far more energetically than within the organism, and if cured replanted in the patient. A thyroid extirpated in the course of an operation ... a kidney removed for tuberculosis, or a leg amputated for osteosarcoma, would perhaps heal under the influence of an artificial medium when living in vitro. The replantation would offer no difficulty, as surgical techniques for the suture of blood vessels and the transplantation...
...hear scientific talk of "giant molecules." But molecules, infinitesimally tiny as they are by ordinary standards, vary greatly in size. Molecular weight of ethyl alcohol, for example, is 46 units; * of sodium chloride (salt), 58.5; of the hormone secretin, 5,000; of hemoglobin, about 68,000; of the thyroid substance thyroglobulin, about 700,000. Dr. Wendell Meredith Stanley and his associates at the Rockefeller Institute have crystallized the virus which causes mosaic disease in tobacco, found that it weighs 17,000,000 units (TIME, Nov.15). A rabbit wart virus was found to weigh 20,000,000 units, a horse encephalitis...
...Persons from inland Europe are brachycephalic or short-headed, while their children reared in New York and Boston become much more long-headed or dolichocephalic. This reaction may be due to the more favorable physiological action of the thyroid gland in a maritime environment, since the inland Continental regions are so frequently low in surface iodine and thyroid disturbances are prevalent...
...same thing as Vitamin C. To further these studies, Dr, Szent-Györgyi needed large quantities of ascorbic acid, and his pursuit of it took him to a half-dozen European universities and the Mayo Clinic at Rochester, Minn, where Dr. Edward Calvin Kendall, isolator of thyroid hormone and analyzer of adrenal cortex hormone, provided him with a big stock of adrenals fresh from South St. Paul stockyards. He still was not able to get enough to permit all the experiments he wanted to do on the acid's medical effects, and in despair Dr. Szent...