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Word: tightener (lookup in dictionary) (lookup stats)
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...drug users mature, geriatric biology and life circumstances tend to tighten the drugs' hold. Reduced body mass, slower metabolism and less efficient kidneys and liver mean that the same quantity of drug hits harder and stays in the body longer. Older users who think they're keeping their doses fixed are thus, in effect, steadily increasing them. What's more, the loss of a spouse or job or merely the boredom of retirement could tip the nonuser into experimentation and the borderline user into full-blown addiction. Moses, 57, never touched heroin until 2001, when his wife died. But when...

Author: /time Magazine | Title: Balding, Wrinkled, and Stoned | 1/15/2006 | See Source »

...impressionable, but not to being hypercredulous simps. His first two tactics for system-beating, his Vague Generalities and Artful Equivocation, seem to presume the latter, and are only going to convince Crimson-reading graders (there are a few and we tell our friends) that the time has come to tighten the screws just a bit more.Think, Mr. Carswell (wherever you are), think, all of you: Imagine the situation of your grader. (Unless he is of the Wheatstone Bridge-double differential CH3C6H2(NO2)3 set. These people are mere cogs; automata; they simply feel to make sure you have punched...

Author: By A Grader, | Title: A Grader’s Reply | 1/12/2006 | See Source »

...People who are focused too much on the result are going to worry and get nervous and tighten up,” he said. “But if they’re in tune with the process of what’s going on, they’re going to end up doing much better...

Author: By Malcom A. Glenn, CRIMSON STAFF WRITER | Title: Haggerty To Hang Up His Spikes | 1/10/2006 | See Source »

Before heading to Congress, Republican J.D. Hayworth of Arizona was a sportscaster with a signature home-run call: "It's vapor!" Now the conservative Hayworth, 47, is making a similar charge about President Bush's plan to tighten the border with Mexico and establish a limited guest-worker program. He is about to publish an anti-immigration manifesto, Whatever It Takes, that should rile up right-wing radio just as the White House was hoping to gain traction for a broad immigration-reform package...

Author: /time Magazine | Title: Blocking Bush at the Border | 1/1/2006 | See Source »

...finished with 27 saves, stonewalled Johnston, freshman Sarah Wilson, and senior Jennifer Raimondi all from point blank range. Boe, meanwhile, stifled several odd-man rushes and a strong drive from Friars captain Karen Thatcher. Boe totaled 28 stops on the night. “Down the stretch, things tighten up, become more defensive-minded,” Stone said. “I think [Boe’s] a little tired. She doesn’t know it yet, but she’s getting a breath this weekend,” she added. The bright spot for Harvard...

Author: By Jonathan Lehman, CRIMSON STAFF WRITER | Title: Harvard Edges Friars to No. 10 Spot | 12/1/2005 | See Source »

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