Word: tigres
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Freed from the confines of the NIH, Venter took an offer from a venture capitalist to head his own research facility, which he named The Institute for Genomic Research--TIGR, or "tiger." The private sector gave him the resources to find genes as fast as he could...
Today, four years later, a total of 20 genomes have been fully decoded, 10 of them at TIGR. In December scientists at Washington University in St. Louis, Mo., and at the Sanger Centre passed a new milestone by decoding the first animal genome, that of a tiny roundworm, Caenorhabditis elegans. At 97 million letters, C. elegans' genome is by far the most sophisticated ever sequenced. But if Venter's newly formed Celera (derived from the word celerity, which means swiftness) can pull it off, his proposal to shotgun the entire 3 billion-letter human genome in three years will make...
Venter says he can do the job faster, cheaper and just as well. In May he announced a joint effort between his center, the Institute for Genomic Research (TIGR) and Perkins-Elmer Applied Biosystems that he says will decipher virtually the entire human genome in three years and cost less than $300 million...
Then the real work begins. Using new software developed by TIGR scientists, Venter's team will begin solving the world's biggest jigsaw puzzle: reassembling those millions of pieces into a coherent whole. It's a daunting task, and some scientists have grave doubts about whether Venter...
Venter exudes confidence and points to TIGR's track record. Using the shotgun approach, his company has already sequenced the DNA of seven microorganisms, including the bacterium that causes ulcers. That number, he notes, represents half of all the genomes decoded to date. "The [human] genome will be accurately and completely covered," Venter promised the science subcommittee last week. And as proof he promised to sequence the genome of the fruit fly (which is far more complex than those of bacteria) within a year...