Word: tilney
(lookup in dictionary)
(lookup stats)
Dates: during 1980-1989
Sort By: most recent first
(reverse)
Nwither Mudge nor Brigham and Women's heart surgeon and Professor of Surgery Nicolas L. Tilney '58 could say why Bouener continued to reject his heart in spite of treatment with sophisticated immunosupressant drugs...
...However, Tilney said at the time of the operation, only 50 percent of heart transplant recipients could be expected to survive. "There are too many variables to be able to predict whether or not a patient will accept the new heart, but Boucher was moribund; he would have died [much earlier] without the operation...
...practical purposes there is not evidence to suggest that a xenograph [species-to-species] transplantation could be successful," Professor of Medicine Nicholas L. Tilney '58, one of several doctors to conduct the first heart transplant in New England, says after Baby Fae's death. "There is no biological evidence to suggest that the immune system could be sufficiently supressed to subdue the baby's rejection of the heart, and there must be some biological evidence before one can conduct on operation...
...extremely suppressing that she survived as long as she did," says Tilney, adding however that he attributes this to the immaturity of Baby Fae's immune system and her increased tolerance for foreign organs as a neo-natal and not the success of the operation. "She couldn't recognize the difference between herself and the other and thus did not reject the heart as quickly as an adult would have...
Medical researchers, however, have convincing arguments for the need to use animals. "You can't name a significant medical advance in the last fifty years which hasn't used animals in experimentation to a certain extent," Tilney explains. He says that sacrifices are necessary for the continued progress of medical science...