Word: tjio
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Dates: during 1960-1969
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...Tjio (pronounced Chee-o), 43, now at the National Institutes of Health in Bethesda, Md., a citizen of The Netherlands and a native of Indonesia. While doing cancer research at the University, of Lund in Sweden, Tjio...
...cells to get a far clearer picture of the chromosomes inside them than had ever been available before. They counted and recounted the chromosomes. The total came to only 46 -though for 30 years scientists had been certain that the human species had 48. Touched off by the revolutionary Tjio-Levan discovery, six hectic years of work on chromosomal abnormalities have already revealed clear links with some physical and mental disorders. Dr. Tjio got a personal award of $8,333 but no cash for his research, because the U.S. Government is already financing...
...rome Jean Louis Marie Lejeune, 36, of Paris, went to work with Tjio's techniques and soon found that victims of mongolism, who suffer varying degrees of mental retardation, have 47 chromosomes. Dr. Lejeune also reported recently that mongoloids have a metabolic abnormality that works in the opposite way from phenylketonuria. Partly because of the extra chromosome, their systems produce too much of an enzyme that breaks down tryptophan, an essential component of proteins involved in the functioning of the brain. Dr. Lejeune's award: $8,333, plus $25,000 for research...
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