Word: tnp
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Dates: during 1990-1999
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However, according to Moulton, another drug tested in Folkman's lab, TNP_470, has similar effects as endstain on retarding plaque buildup and is being used in human trials. Moluton said she is interested in continuing research on heart disease to investigate the mechasnism behind the success of endostain and TNP...
About 10 years ago, the first inhibitor was discovered. Clinical trials began in 1992 to establish the use of the inhibitor--TNP-470--as a cancer drug, largely as an adjunct after chemotherapy...
...Tumor growth could be slowed significantly, but not reversed [using TNP-470]," Folkman said. "Nevertheless, for the first time, there was no drug resistance...