Word: tocopherol
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Dates: during 1940-1949
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...cases where the blood clots quickly, an anti-clotting agent to slow the process might be the answer. But Ochsner warned that such agents are "too dangerous." His suggestion: alpha tocopherol phosphate, "a normal antithrombin found within the blood [which] appears to represent a satisfactory substance to correct an antithrombin deficiency...
...addition, iron added to the prematures' diet to prevent anemia destroys vitamin E. While practically nothing is known about the workings of vitamin E in the human body, this was a lead worth following up. The Owenses arranged to get a special preparation, d-1 alpha tocopherol acetate, rich in vitamin E, to be given in a water base...
...since by that time irreversible retinal changes have occurred." Thus in the case of the Hoffmann twins, it apparently was several months too late for vitamin E treatment when the babies were brought to New York. At Johns Hopkins, every baby under three pounds now gets alpha tocopherol when a week old, and until it passes the 5½-pound mark...
...Tocopherol (vitamin E) and methyl naphthoquinone (equivalent of vitamin K) complete the list of the vitamins that are available from chemical manufacture. They are still little used. The former is essential for reproduction in rats, so that it has become known as the sex vitamin, but doctors are still uncertain whether it has any such value in human beings. The latter is unique: it is not vitamin K but is equally effective in decreasing the clotting time of blood...
...alpha tocopherol, is found in green leaves, wheat germ...