Word: toed
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Dates: during 2000-2009
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“We were trying to sabotage them by figuring out what they’re actually using and taking it away,” said Elledge, who is also a senior geneticist at Brigham and Women’s Hospital.
The researchers, who had already used this same process in studies of HIV and the hepatitis C virus, hoped to find that some of the treated cells could not be infected with the influenza virus, which would suggest that the virus needed the deactivated gene to function. Instead, the researchers...
“There’s a certain level of it in your cells all the time preventing 80 to 90 percent of all infections,” Elledge said. “If you get rid of those genes, you see nine or 10 times more infections.?...
Brass and Elledge said that they next seek to determine how IFITM works in preventing the flu. For now, the discovery of these native anti-viral proteins may bode well for the battle against influenza.
A drug that increases the presence of IFITM proteins in humans without provoking negative side effects may be an effective means of preventing influenza. Another area of potential research is the possibility of inserting the IFITM genes into the genomes of animals like swine and poultry—the strains...