Word: tofranil
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Dates: during 1960-1969
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...those most widely used, four apparently work by a double-negative action, blocking an enzyme that breaks down brain-stimulating substances: isocarboxazid (Marplan), nialamide (Niamid), phenelzine (Nardil), and tranylcypromine (Parnate). Drugs with similar anti-depressant effects are imipramine (Tofranil) and amitriptyline (Elavil). All are prescription drugs, and should be taken only under close medical supervision...