Word: torcetrapib
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...more HDL. They also have an added incentive to prescribe the powerful statin drugs that lower LDL because those appear to do double duty, pumping up HDL levels 10% to 15%. And if that isn't enough, they are eyeing the arrival of HDL-boosting pills: Pfizer's torcetrapib is currently in clinical trials in combination with a statin and could be ready for FDA review in a year or two. "It's a look into the future of heart care," says Dr. Roger Blumenthal, director of Johns Hopkins Hospital's preventive cardiology program, of the new focus...
...take a drug to lower their LDL, or bad cholesterol, but if things go Pfizer's way, they may end up adding a pill that raises HDL, the good cholesterol that helps keep arteries clean. A study in the current New England Journal of Medicine reports that the drug torcetrapib boosted HDL levels 46%. When it was combined with the LDL-lowering drug Lipitor, the results were even more dramatic: HDL levels rose 61%, and LDL fell even more than it did with Lipitor alone. But will raising HDL levels mean lower rates of heart disease and fewer deaths? That...
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