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...then, astonishingly, it did. In June 2006 a modest researcher from Japan made a startling announcement at the International Society for Stem Cell Research conference in Toronto. Shinya Yamanaka quietly described a study in which he took skin cells from a mouse and stirred them in with varying genetic cocktails made from a recipe list of 30 genes known to be important in development. When he hit on the right four genes and inserted them into the cells aboard retroviruses, he wiped the cells clean, reprogramming them and returning them to an embryo-like state without ever creating the embryo...

Author: /time Magazine | Title: Stem-Cell Research: The Quest Resumes | 1/29/2009 | See Source »

...roll, with breakout hits like Little Miss Sunshine and Juno. Searchlight president Peter Rice saw the magic the movie had on its viewers: "It's like they've discovered such a unique experience, they immediately want to share it with other people." Late-summer screenings at the Telluride and Toronto film festivals got a rapturous response, and Searchlight quickly pegged it as a November release, with eyes on critics' awards and the Oscars. (Warner retains a share of revenues.) It all worked perfectly. (See the 100 best movies of all time...

Author: /time Magazine | Title: From Slumdog to Top Dog | 1/29/2009 | See Source »

...ever feel like a dirty old man? Lisa Pearl, TORONTO...

Author: /time Magazine | Title: 10 Questions for Hugh Hefner | 1/15/2009 | See Source »

...study - which included 7,688 patients in eight hospitals around the world - saw death rates drop from 1.5% before the checklist was instituted to 0.8% afterward. Serious complications fell from 11% to 7%. Study sites included Seattle, London, Toronto, New Delhi, and Ifakara, Tanzania. (See TIME's A-Z Health Guide...

Author: /time Magazine | Title: Study: A Simple Surgery Checklist Saves Lives | 1/14/2009 | See Source »

...started with the Oakland A's in 1979 (and still holds his greatest loyalty for the team - he left and came back three separate times). Over the next 20 or so years, he played for the New York Yankees, the Toronto Blue Jays, the San Diego Padres, the Anaheim Angels, the New York Mets, the Seattle Mariners, the Boston Red Sox, and the Los Angeles Dodgers. Was a 10-time All-Star and the 1990 American League...

Author: /time Magazine | Title: Rickey Henderson | 1/13/2009 | See Source »

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