Word: tortuous
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Dates: during 1980-1989
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...solve the problem, Langer and his colleagues reconfigured the structure of polymers to enable drugs to be dispensed in measured doses. Explains Langer: "Because its route is so tortuous, the drug gets out, but slowly." Langer is now testing an injectable system for diabetics in which enzymes sensitive to glucose in the bloodstream are placed in microscopic polymers along with insulin. The drug is released through the complex, porous polymer structure. Because the solubility of insulin increases in the presence of glucose, the more glucose in the blood, the more drug is released. This "intelligent" method represents a potential revolution...
CALVINO tackles questions that have puzzled the driest and most difficult literary critics of the century, but he does not share their obsession for inventing or redefining terms. He does not bully the reader with tortuous grammar, or leave gaps and ambiguities in his logic as examples of the defects in language itself; his sentences are clear and simple. "There is a lightening of language," Calvino posits, "whereby meaning is conveyed through a verbal texture that seems weightless, until the meaning itself takes on the same rarefied consistency...
Clarkson's path to the ECAC semis came through the tortuous backroads of Ithaca, N.Y., where the Knights met Cornell in the quarters a week ago. The two clubs split a pair of playoff games, and then the Knights prevailed, 1-0, in a 10-minute mini-game that followed the end of the second game...
...faces like chimney sweeps exchange tales of close calls and prior battles. Their constant coughing sounds like a tuberculosis ward. As they talk, each fire takes on its own mischievous personality, some quick and cagey, others plodding and stubborn. Despite the laughter, some fire fighters appear homesick. The constant, tortuous line at the only two available pay phones is full of long faces. After waiting for 2 1/2 hrs. to call his wife, one man is greeted by an answering machine, and his howls echo through the smoke as he storms back to his tent...
AFTER FIVE years of sometimes tortuous soul-searching, the Undergraduate Council seems to have found itself...