Word: toxicants
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While Spencer's discovery cannot directly explain the cases of the San Francisco 49ers or the Ohio schoolteachers, it does lend credence to the notion that something toxic in diet or environment can later trigger ALS. Indeed, over the years, a befuddling array of culprits has been suggested. They include infection with poliovirus, exposure to heavy metals, employment in the plastics industry and a history of traumatic injuries...
Unfortunately, AZT is not a cure and has a number of serious drawbacks. It must be taken every four hours around the clock to be effective, and can cause severe bone-marrow damage and anemia in some patients. "It's not an answer, and it's very toxic," says Polk, of Johns Hopkins. "Probably half of our patients on AZT will require weekly or bimonthly blood transfusions...
Perhaps the most promising of the dozens of other AIDS drugs under development is dideoxycytidine (DDC), which belongs to the same category of drugs as AZT. Like AZT, it works by interfering with viral reproduction, but researchers hope it will prove to be less toxic. Hoffmann-La Roche expects to receive a license to manufacture the drug within the next few months...
...North Cambridge activist, chairs the Cambridge Committee of Elders and Cambridge Toxic Alert. He says he will attempt to win victory by securing a firm minority of voters rather than presenting a broad city-wide appeal...
After two weeks of ferocious shelling by Iranian forces, Iraq's besieged southern port city of Basra is becoming a ravaged wasteland of damaged buildings and pockmarked streets. Toxic gas has engulfed an area south of the city where Iranian artillery barrages set fire to a petrochemical complex. Demoralized and frightened, thousands of the city's 1 million residents have reportedly fled north to the capital of Baghdad in cars, on bicycles and on foot. Said a U.S. official: "If there is a victory in this for the Iranians, it is that they have been able to create the impression...