Word: toxicities
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...important as what you eat. Americans are fixated on nutrients, good and bad, while the French and Italians focus on the whole eating experience. The lesson of the "French paradox" is you can eat all kinds of supposedly toxic substances (triple crme cheese, foie gras) as long as you follow your culture's (i.e., mother's) rules: eat moderate portions, don't go for seconds or snacks between meals, never eat alone. But perhaps most important, eat with pleasure, because eating with anxiety leads to poor digestion and bingeing. There is no French paradox, really, only an American paradox...
...grabbed headlines and changed the way doctors think about treating cancer. Because Gleevec was exquisitely targeted to interrupt a specific step in the cancer cell's growth process, it heralded a new era of kinder, gentler treatments that would pack all the anti-cancer wallop of chemotherapy without the toxic side effects...
...drug in human patients, which usually involve a handful of the sickest patients who have not responded to standard treatments. The purpose of Phase I studies is to establish what's known as the maximum tolerated dose - that is, the dose at which the drug then becomes too toxic and dangerous to take. But because the number of patients is too small and the safety of the drug hasn't been established, such tests are not designed to determine the drug's effectiveness...
...economic logic behind dumping a load of toxic waste in the lowest-wage country is impeccable” could serve as the epitaph for the presidency of University President Lawrence H. Summers. While his supporters might defend this infamous phrase in the name of “freedom of expression” or excuse it as an unfortunate slip, critics find it typical of a carelessness of expression that mocks both logic and human decency—a carelessness that pursued him into his presidency.There is much public confusion over why Summers resigned, and the speculations are a Rorschach...
...processes that allow the body to turn food and air into nourishment for individual cells also create by-products that amount to toxic wastes--highly reactive oxygen molecules known as free radicals that can combine with otherwise innocent substances and transform them into killers. Free radicals may be responsible in part for the genetic damage that leads to some cancers. And they also appear to be what makes LDL and triglycerides so dangerous. When a free radical combines with one of these fatty molecules, the altered cholesterol turns into a biochemical cannonball that ricochets around the bloodstream, damaging the inner...