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...world heralded Hwang, who reported that he had created the world's first human embryonic stem cells using a delicate cloning technique called somatic cell nuclear transfer (SCNT). If Hwang had actually done what he had claimed, he would certainly have brought stem-cell-based therapies closer to reality, by making it possible to develop patient-specific cells to treat diseases from diabetes to Parkinson's. Two years after his announcement, however, allegations of fraud led to an investigation by an independent committee of scientists, which failed to verify his findings, and Hwang and his feat were discredited; last year...

Author: /time Magazine | Title: Korean Cloner Redeemed... Sort Of | 8/2/2007 | See Source »

...line contains the first human cells to be generated not through SCNT, but through a process called parthenogenesis, sometimes referred to as virgin birth, since development is sparked spontaneously from the egg alone, rather than from the union of egg and sperm. Parthenogenesis is always a risk during nuclear transfer, since the process involves extensive manipulation of the egg and its nucleus. At the time that Hwang's original paper was published in Science, stem cell researchers raised the possibility that the cells had been generated by the egg alone, but the limited genetic analysis that Hwang provided appeared...

Author: /time Magazine | Title: Korean Cloner Redeemed... Sort Of | 8/2/2007 | See Source »

...Renee Reijo Pera, director of the center for human embryonic stem cell research and education at Stanford University, agrees. "Hwang's actions were a great setback mentally for the nuclear transfer community," she says. "He really would have been far ahead of the rest of the field by just reporting these lines as parthenogenetic; they could have reported these legitimate results and been scientific heroes...

Author: /time Magazine | Title: Korean Cloner Redeemed... Sort Of | 8/2/2007 | See Source »

...nuclear transfer, stem cells are created by inserting the nucleus from a donor's cell, usually a skin cell, into an egg cell, whose DNA-containing nucleus has been removed. The new cell then starts to divide and produce stem cells. In some cases, however, through mistakes in the nuclear-transfer process, eggs may begin dividing on their own. And Hwang may have increased his chances of parthenogenesis by using the gentler, squeezing technique he pioneered to remove the egg's nucleus; the process may have actually left behind enough genetic material for the egg to spontaneously divide...

Author: /time Magazine | Title: Korean Cloner Redeemed... Sort Of | 8/2/2007 | See Source »

...economy. Even the offshoring of white-collar jobs, despite the hardship it brings for laid-off workers, is a net gain for developed nations like the U.S. and Japan, as well as for the country where the jobs land. Every dollar of spending that U.S. companies transfer to India creates $1.46 in new wealth, according to McKinsey & Company, a management consultancy...

Author: /time Magazine | Title: Coping Strategies | 7/19/2007 | See Source »

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