Word: transplanter
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...infected patients, focusing instead on treatment and prevention. But in an announcement that caused a flutter of excitement and a wave of prudent skepticism, Berlin-based hematologist Gero Huetter claimed on Thursday that he has cured an HIV infection in a 42-year-old man through a bone-marrow transplant...
...patient, a U.S. citizen living in Germany, was suffering from advanced leukemia and HIV two years ago when Huetter treated the cancer with a bone-marrow transplant at Berlin's Charité hospital. As a side experiment, he inserted the bone marrow of a donor naturally resistant to HIV, the virus that causes AIDS. (Researchers have long known that about 1% of Europeans carry a genetic mutation that makes their cells resistant to HIV infection.) Bone marrow produces the cells that HIV attacks. So, the thinking went, inserting marrow that produces HIV-resistant cells might endow the patient with...
...there might be a glimmer of hope in the case. If the transplant does prove to have been a success and can be replicated, researchers say gene therapists might one day be able to re-engineer a patient's cells to change their bone marrow the same way a transplant does, except without the dangers. Such a breakthrough, if it proves possible, would be "decades rather than years away," according to Ade Fakoya, a London-based clinician and senior adviser to the nonprofit Aids Alliance. The treatment would also likely prove too expensive to implement in developing countries where...
...span of a month. Bonnie Hubley, his wife, had polycystic kidney disease, in which cysts grow in the kidneys, often becoming so large that the kidneys fail and have to be replaced. All of the Hubley children inherited the genetic disease. In 1995, Bonnie had a kidney transplant, and in October of last year, her body began to reject the replacement kidney, requiring her to start dialysis...
...expected to hit the market with a $250,000 price tag. Some experts say that Carpentier's direction of the project provides enough reason for hope. "He is a genius in his field and an internationally respected figure, both as a developer of devices as well as a transplant specialist. Carpentier brings a lot of authority and gravitas to this," says Dr. Gardner. "Predicting success would be premature, but the fact this is Carpentier's project increases the chances it may constitute a big breakthrough...