Word: transplanters
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Dates: during 1970-1979
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Archie Bunker seeks sexual fulfillment with a waitress. Rhoda and Joe bust up. Charlie Haggars undergoes television's first testicle transplant. Maude's Arthur goes bankrupt. Ted Baxter has a heart attack in mid-newscast. Lionel Jefferson marries Jennie. Florida loses her husband. McMillan loses his wife, his sidekick and his housekeeper...
...result, researchers are stepping up the hunt for a better way. One of these is Surgeon-Immunologist Felix Rapaport of the New York University Medical Center, who became the Transplantation Society's new president-elect last week. Prior to implanting new kidneys in beagles, he has been removing some of their bone marrow-the site, along with the lymph nodes, of white-blood-cell production-and irradiating the dogs. The X rays destroy the ability of the remaining bone marrow and lymphoid tissue to produce white blood cells. Then he reinjects the marrow cells, thus restoring the animal...
Rapaport notes that some of the early kidney transplant recipients, including Riteris, were in fact also irradiated. But in most cases the technique proved unreliable-in part because of uncertainties about how much X-ray dosage the body could withstand-and was thus abandoned. Rapaport believes, however, that his dog experiments now indicate that these problems could be solved, and that irradiation, plus bone-marrow reconstitution, may eventually offer a way of eliminating troublesome immunosuppressive drug therapy in human transplant recipients as well...
...fetus, yet somehow manage to tolerate this "foreign" tissue in their bodies. He therefore wondered whether the baby might actually be stimulating the production of "blocking antibodies" within the mother that neutralize her immune reaction against the fetus. If so, perhaps the same response could be artificially produced in transplant recipients...
...gamma globulin from human placentas, which are usually discarded after delivery, into patients at the hospital's Rogosin Kidney Center. He hopes that the placental extract will transfer blocking antibodies into them. That then might encourage acceptance of new organs. A positive sign: when Riggio examined long-term transplant survivors at the center, he found that their acceptance of kidney grafts somehow appeared to have been enhanced by a biochemical mechanism similar to that postulated in pregnant women...