Word: treatment
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Dates: during 1990-1999
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...going to cure cancer. Cancer is a complicated disease. Tumors usually are made up of different types of cells, expressing different genes, sensitive to different growth factors and therefore responding to different drugs. "When you are trying to kill cancer cells, you're always likely to need combination treatment," says Merck's Scolnick. Like AIDS treatments, the new generation of cancer drugs will need to be combined with older drugs and possibly with one another to be most effective...
...promise of these drugs holds up, however, cancer treatment in the 21st century will bear little resemblance to today's chemotherapy. Drugs will be precisely tailored to the individual tumor, and the cancers themselves will be described not by the site they attack--breast cancers, lung cancers, etc.--but by the genes they express. The National Cancer Institute is at work creating a DNA library of tumor types, a long-range project called C-GAP (Cancer Genome Anatomy Project). But it will be years before this library can be put to practical use. "It took 20 years to make testing...
Looking back at TIME's extensive coverage of cancer helped me put this hope and frustration into perspective. In 1949 we did a cover on cancer fighter Cornelius Rhoads, whose Sloan-Kettering Institute had tested 1,500 chemicals on mice in hopes of finding "chemotherapy" treatments. In a cover 10 years later, we predicted that "drug treatment will emerge as the equivalent of surgery and radiation," and quoted the National Cancer Institute's John Heller as saying, "I'm confident that we will have some success in the next few years...
HILLARY CLINTON Gives opinion on Mideast, gets Mission: Impossible treatment: "The White House disavows...
Patience is the last thing you can reasonably ask of someone who's in the final stages of terminal cancer. For these people and their families, talk of safety and efficacy and extended double-blind trials are just so much noise. A treatment that may be available five years from now or next year or even in a few months amounts to no treatment at all. So what if angiostatin and endostatin work only in mice? If there's even a minuscule chance the compounds will cure cancer in humans too, why should the dying have to wait another minute...