Word: treatments
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Dates: during 1990-1999
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When fenfluramine was approved in 1973, the FDA declared it safe for short-term use. The assumption: that it would be prescribed for only severely obese patients who seemed impervious to other treatment--"not," as University of Pennsylvania cardiologist Frank Silvestry puts it, "to get into a bikini or wedding dress." But in 1992 all that changed. Studies showed that if fenfluramine was taken with a kindred drug, phentermine, the euphonious fen/phen duo would help dieters shed pounds not only faster but with few side effects. Although the drugs were never approved for combined use, doctors exercised their right...
...advocacy group Public Citizen charge that some U.S.-sponsored AIDS-research projects in Africa are unethical. The Journal's editor, Dr. Marcia Angell, goes even further, comparing these studies to the infamous Tuskegee experiment in which black men in the South were deliberately deceived and denied effective treatment in order to determine the natural course of syphilis infection. This comparison is inflammatory and unfair, and could make a desperate situation even worse...
...novel psychological theories of the great (and imaginary) psychiatrist Dr. Laszlo Kreizler seem a bit further from the center of things here than they did in The Alienist. True, he affronts received opinion by postulating that a woman, because of her treatment in childhood, may be quite capable of murdering her own children and those of others. He helps trap the woman he has described. But for the trial to go forward he must declare her sane, a judgment that would have seemed as mushy at the beginning of the Freudian era as it does now. For a long stretch...
LIFEBLOOD Children with sickle-cell anemia who are at high risk for stroke can benefit from a new treatment. Monthly blood transfusions reduce their rate of stroke...
...chemical cocktail that has proven so effective in fighting HIV? The announcement to this effect by Dr. Steven Deeks, a University of San Francisco AIDS researcher, that people might be developing an immunity to the protease inhibitors Crixivan and Norvir has left many questioning whether the highly-expensive treatment would remain worthwhile. A study of 136 HIV-positive people who started using the inhibitors in March of 1996 showed that within a year the virus had returned to detectable levels in about 53 percent...