Word: trialing
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...possible that the nocebo response is easily explained: in the antidepressant trials, maybe some patients - given that they already tended toward depression and anxiety - worried so much about the doctor's cautions that their stomach released enough acids to cause pain. That would make sense except that the range of possible nocebo responses stretches far beyond stomachache (in extreme cases, ailing patients who are mistakenly informed that they have only a few months to live will die within their given time frame, even though postmortem investigations show that there was no physiological explanation for early death). In a new paper...
...appeared to have, says Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases. "When you lose statistical power, something that would have been significant in the [original, larger] population, could now fall below significance merely by the lower numbers. That's what happened with this trial," Fauci says...
According to Fauci, however, the trial was not designed to license the vaccine but to test whether the concept of using the two vaccines in sequence would work. In the latter condition, statisticians say scientists generally consider all data from the complete, original population, since these numbers more accurately reflect what might happen in the real world. In other words, it's a more rigorous analysis of how effective a vaccine might be in a population of people who, realistically, could be exposed to HIV before they finish the full six doses of the vaccine...
...Also keeping his distance from the trial is Mbeki. Mbeki was ousted by Zuma as leader of the ANC nearly two years ago following a lengthy power struggle in which the rivals fought numerous battles in the courts. Zuma faced accusations of rape and corruption (he was acquitted of the first, and charges in the second case were dropped). Mbeki, meanwhile, was badly damaged by his association with Selebi - and his reluctance, even as Selebi's legal problems deepened, to censure him. (Read "Thabo Mbeki: The Dream Deferred...
...Although Selebi's trial signifies a step forward in prosecuting allegations of corruption in South Africa, few expect it will do much to clean up the country's politics. With the prosecutor's dropping the corruption case against Zuma weeks before he was elected, the allegations against him remain unresolved. And while Zuma has taken pains to include a broad spectrum of leaders from different parties and factions within the ANC in his Cabinet, his appointment earlier this month of Mo Shaik to head South Africa's intelligence service raised a few eyebrows. Shaik's brother Schabir Shaik was convicted...