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...fish killed and infected, as many as 28 people who have come into contact with the water have developed symptoms including skin rashes, respiratory problems and memory loss. The culprit appears to be an obscure microbe called Pfiesteria piscicida, which under certain circumstances turns toxic. Though the precise trigger remains unclear, suspicion has fallen on agricultural runoffs, particularly from the region's numerous chicken farms. In addition to closing waterways, Governor Parris Glendening has named a panel to investigate the runoff problem and has called a summit of Governors from surrounding states to consider regional solutions...

Author: /time Magazine | Title: MASSACRE ON THE BAY | 9/29/1997 | See Source »

...such popular antidepressants as Elavil, Prozac, Zoloft and the hot new herbal medication St. John's wort; powerful appetite suppressants including Redux and fenfluramine; and antipsychotics such as clozapine. Like every other drug, the ones that zero in on serotonin have side effects. Elavil makes people sleepy. Zoloft can trigger headache and nausea. Zoloft and Prozac may cause sexual dysfunction. All these symptoms are annoying, to be sure, yet they are a price that many sufferers have been willing...

Author: /time Magazine | Title: THE MOOD MOLECULE | 9/29/1997 | See Source »

...last week it became startlingly clear that monkeying with the chemistry of the human mind can trigger problems much more serious than a dull sex life. Just 1 1/2 years after it approved Redux for treatment of obesity, the FDA issued a warning advising patients to stop taking it and its close chemical cousin fenfluramine immediately. At the same time, the drugs' manufacturers and distributors, Wyeth-Ayerst Laboratories, told physicians to stop prescribing them and took the dramatic step of pulling both medications from the market. The reason for such haste: new evidence had revealed that as many...

Author: /time Magazine | Title: THE MOOD MOLECULE | 9/29/1997 | See Source »

...first, the effects of serotonin seemed confined to the body alone: it was found to trigger contractions in the muscles and intestines and to regulate blood pressure by forcing blood vessels to constrict. But experiments at the National Institutes of Health in the 1950s revealed that compounds that depressed serotonin levels depressed patients as well. Not long after, researchers found two more clues to the serotonin-depression connection. The first was that reserpine, an anti-blood-pressure medicine that depresses serotonin levels, can sometimes trigger depression. The second came from iproniazid, originally developed as an anti-tuberculosis agent. The medicine...

Author: /time Magazine | Title: THE MOOD MOLECULE | 9/29/1997 | See Source »

...least, injecting a weakened strain of the virus. The activists-turned-guinea-pigs petitioned the National Institutes of Health Monday to allow them to be the first humans to receive live HIV vaccinations. TIME health reporter Christine Gorman says there is proof "that this vaccine could trigger a stronger immune response than other kinds of inoculations." On the other hand, Gorman warns the shots are not magic bullets: "There are cases where the virus has reconstituted itself and produced an HIV infection. Some strains might even give recipients cancer at a later date." The rewards are great...

Author: /time Magazine | Title: Risky Twist to AIDS Research | 9/22/1997 | See Source »

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