Word: trimethyl
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Dates: during 1930-1939
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...William Russell Levis & Edward Lewis Axelman of Philadelphia call theirs a "Modern Method for Prevention of Postoperative Distention." They depend upon a newly synthesized drug to keep the bowels moving and expelling any gas which may form. The drug: dimethyl-carbamic ester of 3-hydroxyphenyl-trimethyl ammonium methyl-sulphate, a chemical compound which has been telescoped to prostigmin. Drs. Levis & Axelman inject small amounts of prostigmin "at the time of operation or shortly thereafter and continue injections for 24 to 48 hours at four to six hour intervals, or until such time that we feel the condition of the patient...
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