Word: trounson
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...Trounson's method, called immature oocyte collection, is radically different from traditional IVF. Instead of priming the woman with fertility drugs so that eggs (the oocytes) will mature, doctors simply remove immature eggs. The timing is no longer crucial. Success hinges on two new techniques: locating the immature eggs and stimulating them to mature outside the ovary...
...process begins with an examination of follicles, the tiny sacs in the ovary where eggs are found. Fertility doctors ordinarily focus on large follicles -- nearly a half-inch wide -- that contain mature eggs. But Trounson's partner, Dr. Carl Wood, discovered that the latest ultrasound machines could spot follicles that are less than a tenth of an inch wide and hold immature eggs. Wood developed a way to pluck the young eggs out of the smaller follicles with a specially designed needle. Trounson, after experiments with cattle, devised a cell-culturing procedure that ripens the immature eggs in the laboratory...
Robyn Hallam, 33, was a perfect candidate for the new, streamlined IVF. Unable to conceive naturally with her husband Tim, a grain farmer in Hopetoun, Australia, Robyn tried fertility drugs to no avail. As the couple prepared to undergo traditional IVF, they were offered Trounson's new approach. "We were told that there'd never been a baby born through this procedure," Robyn recalls. "We thought, 'What do we have to lose...
...drug treatments and monitoring, Robyn merely went to the Monash clinic to have immature eggs extracted. The doctors got six eggs and tried to fertilize them all, but only one developed into a viable embryo. It was implanted in Robyn's womb, and on Dec. 14, 1993, Kezia Hallam, Trounson's first bundle of success, was born...
...Trounson and the Monash team, in contrast, have impregnated several more women. IVF America, a Greenwich, Connecticut, company associated with Monash, plans to develop the technique...