Word: tryptophane
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...amino acid glutamine onto the protein chain rather than stopping production; it obeyed only the third word for stop, TGA. At Nagoya University in Japan, scientists have found that Mycoplasma also ignores a stop triplet. But in this case it is TGA that is translated into an amino acid, tryptophan, while the other two codons are read as stop. "Within a certain sphere," says Biologist Syozo Osawa, "it seems that change is possible...
...City's Mount Sinai Hospital identified the condition that ended her career: myoclonus, a nervous disorder that affects only 2,000 Americans. Van Woert had received a series of grants and special permission from the FDA to treat the disease with the experimental drug L-5HTP (L5-hydroxy-tryptophan), and Dobkin responded well to it. Within eight months she was able to walk with crutches and a neck brace and begin training for a new career as a medical assistant. Eventually she was well enough to have a child...
Similarly, scientists have found that a low level of the neurotransmitter serotonin may be linked to insomnia. Researchers have been experimenting with tryptophan, the chemical from which the body makes serotonin. Only a small dose of tryptophan-which is found in many foods, notably milk-seems to ease the insomniac to sleep...
...victims of mongolism, who suffer varying degrees of mental retardation, have 47 chromosomes. Dr. Lejeune also reported recently that mongoloids have a metabolic abnormality that works in the opposite way from phenylketonuria. Partly because of the extra chromosome, their systems produce too much of an enzyme that breaks down tryptophan, an essential component of proteins involved in the functioning of the brain. Dr. Lejeune's award: $8,333, plus $25,000 for research...