Word: tsai
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Dates: during 1990-1999
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When finished, the normal six layers which should be present in the cortex were absent and "the distribution of cells seemed random at first," Tsai says...
...mutation caused younger cells to stop and not pass the older neurons. A gradient of increasingly older neurons toward the outside of the cortex resulted, which, according to Tsai, "effectively inverted the pecking order of the cortex...
...This process amazes me, but, in terms of molecular control, no one has the faintest idea what is going on," Tsai says in a newsletter...
...This mutant provides the first evidence that such a signaling pathway exists," Tsai says...
...Although Tsai's research has focused solely on the brains of mice, she says the results are not unique to that species...