Word: tumor
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Dates: during 1980-1989
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HOSPITALIZED. John C. Stennis, 83, Mississippi Democratic Senator and dean of the upper house who eleven years ago survived a mugger's bullet; in satisfactory condition after the amputation of his left leg at the thigh because of an inoperable malignant tumor; at Walter Reed Army Medical Center in Washington...
...past few years a second line of attack has also uncovered oncagenes as scientists have found genes in various tumor cells that can transform them into cancer cells. Presumably, each oncagene was instrumental in generating the tumor from which it was isolated...
Further research has shown that some cells cannot produce oncagenes. But, they still may be able to induce tumor growth by somehow instructing another cell to produce oncagenes and cause cancer...
...achievement of Milstein and Köhler was to fuse a tumor cell with a cell that produced a specific antibody. They thus created a hybrid that not only manufactured the antibody but multiplied as rapidly as the cancer cell. The resulting culture served as a miniature factory, churning out the desired antibody. Because every cell in the culture is an identical descendant, or clone, of the original hybrid, the antibody is pure and therefore a precise instrument. Says Milstein: "It al lows you to discriminate one molecule from another." Monoclonal antibodies can home in on targets ranging from...
...Robert C. Gallo, chief of laboratory tumor cell biology at the National Cancer Institute in Washington, who worked with Groopman in isolating HTLV-III in saliva, said yesterday that the implications of Groopman's work are serious...