Word: tumor
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Dates: during 1990-1999
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Even if that's true, say other scientists, MAP kinases are just one component of an elaborate biochemical network that controls the process of cell division. Though breast tumors may contain high levels of the enzymes, that may well be an effect of malignancy rather than the cause. This does not mean that MAP kinases are not important contributors to tumor growth. But, cautions Susan Braun, president of the Susan G. Komen Breast Cancer Foundation in Texas, "people should understand that this is a piece of the puzzle, not the single answer." Indeed, there will probably never be a single...
...Tumor growth could be slowed significantly, but not reversed [using TNP-470]," Folkman said. "Nevertheless, for the first time, there was no drug resistance...
About two years ago, it was discovered that tumor growth could be slowed almost completely by using normal proteins to signal the vascular endothelial cells which line blood vessels...
...first time, it became possible to shut off angiogenesis and cause [tumor] regression," Folkman said. "This was caused by a specific signal which only talks to endothelial cells...
...well known that some tumors suppress the growth of metastases," Folkman said. "Our question was [that] if tumor size is ultimately controlled by endothelial proliferation, could a primary tumor suppress growth of a distant metastasis by delivering an endothelial inhibitor to it through the circulation...