Word: tumorous
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Mammograms have saved the lives of tens of thousands of women over the past 20 years. Though mammograms are not perfect, their ability to detect small tumors gives doctors and their patients the option of treating the cancer while it is in an early, more curable stage. And yet by the time even a small tumor is picked up on a mammogram, odds are it has been growing for five to seven years. What if doctors could find even younger (and therefore presumably easier to treat) breast tumors? That's the question that a group of researchers asked themselves...
BLOOD TESTS Researchers from the John Wayne Cancer Center in Santa Monica, Calif., are working on developing biological markers that could identify microscopic tumors as they travel through the blood. As many as 20% of women with early breast cancer whose tumor has not, as far as anyone can tell, spread to the lymph nodes have a recurrence of the malignancy after their treatment. Current thinking is that they must already have had so-called micrometastases in their bloodstream and that a blood test might eventually uncover the problem ahead of time. Depending on the result, doctors could then pursue...
...years now, "smart" drugs have been the hottest trend in cancer treatment. They are designed to zero in on the proteins that nurture tumor cells. In the past year alone, the FDA has approved three such drugs (for non-Hodgkin's lymphoma, breast cancer and leukemia). And more are in the pipeline, because scientists are becoming increasingly skilled at designing drugs that target specific, critical molecular processes that tumor cells need to survive. Herceptin, for example, takes advantage of the fact that most breast-cancer cells overproduce a certain growth-factor protein; the drug preferentially seeks out tumor cells...
...have him under wraps for six weeks," says a Democratic strategist. "He'd get the sympathy thing. He'd still be able to raise money. And he wouldn't be able to get himself in trouble." While none of Giuliani's advisers are chomping cigars and saying, "Rudy, this tumor's your friend. Embrace your cancer, Mr. Mayor," they know it offers him a chance to reintroduce himself as someone who has confronted his own mortality and won a deeper understanding of life. "Rudy's got a tremendous amount of compassion, but nobody knows that," says Molinari...
...that stem cells are attracted to injured tissues, perhaps because of biological cues released by dying or diseased cells. Indeed, one of Snyder's lab colleagues found that a batch of stem cells had migrated from one side of a rat's brain to the other to infiltrate a tumor...