Word: tumors
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Dates: during 1960-1969
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...help nail down the indictment last week, Dr. Thomas M. Bell reported from a research center at Entebbe that he has isolated reovirus 3* from seven victims of Burkitt's tumor. This finding alone might well have been pure coincidence, but there was additional evidence: antibody against reovirus 3 has been found in 73% of lymphoma patients, and in only 12% of comparison subjects from the same districts. From Australia came further word: mosquitoes carrying the same type of virus have been found there...
There were as many dissents as there were theories, and since so few drugs cure viral infections, the very fact that potent anti-cancer drugs such as amethopterin (Methotrexate) and cyclophosphamide (Cytoxan) have cured massive cases of Burkitt's supermalignant tumor might seem to argue against a viral cause. But doctors now believe that what the drugs do is cure or relieve a viral-induced cancer, after the virus itself may have vanished. Thus they may give the body an opportunity to develop its own mechanisms to fight the cancer...
...used to be dumped into the catchall category of "cause unknown." Not until the early 1960s was this form found to be caused by an excess of the potent hormone aldosterone (TIME, March 15, 1963), produced by the adrenal glands, which bestride the kidneys. If either gland develops a tumor, it is likely to churn out aldosterone too generously. The victim of this "primary aldosteronism" has too little potassium in his system and usually too much sodium, an imbalance that leaves him prey to intermittent paralysis, uremia-and high blood pressure...
...TIME, June 25) may be explained-why so many patients have a normal or even a high insulin level but fail to metabolize sugars properly. And some diabetes patients will certainly be referred to blood-pressure specialists, who in turn will consult endocrinologists. If the diagnosis of an adrenal tumor is confirmed, a surgeon will then have the difficult job of finding and removing a nodule only about one-sixth of an inch across. After that, suggests Dr. Conn, the patient will lose both his high blood pressure and his misdiagnosed "diabetes...
With medication and a complete cessation of smoking, the accompanying disorders subsided and the operation was successful. "There was little doubt," said Fieser in his letter, "about the origin of these disorders and hence little ground for questioning the origin of the accompanying tumor...