Word: tumors
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Dates: during 2000-2009
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...April 1 issue of the journal Cancer Research, Dr. Timothy M. Browder, an oncologist and Harvard instructor in pediatrics at the Children's Hospital, and a group of his colleagues presented data from a five-year study which sought to examine the effect of targeting a tumor's blood supply rather than the tumor directly...
...data give statistical support to a long-suspected theory that cutting off a tumor's blood supply may shrink it. The article reports that when lower doses of traditional chemotherapy drugs were given more frequently to inhibit blood cell growth--known as angiogenesis--in test mice, 100 percent of drug-sensitive tumors were cured...
...mice whose cancer had become resistant to traditional chemotherapy schedules, the new treatment regimen was three times as effective as the standard regimen in suppressing tumor growth. The standard regimen entails higher doses of chemotherapy drugs, administered less frequently...
...advantage of some of Mother Nature's own ideas to design new chemotherapy drugs. Scientists at Vion Pharmaceuticals of New Haven, Conn., are interested in co-opting a group of Salmonella bacteria that normally attack the intestines and cause dysentery. Salmonella, it happens, also happily infect all kinds of tumors, including colon cancer. By loading genetically crippled salmonella with one of the body's own cancer-fighting chemicals (a molecule called tumor necrosis factor), researchers at Vion hope to destroy or at least shrink a wide variety of cancers. Safety studies in humans are planned for later this year...
...told her doctors about most of her symptoms. But she never talked about the way her stools had changed shape (and she wasn't asked). The pains must be menopause, the doctors decided. Then a year ago, during a flexible sigmoidoscopy, a physician discovered a tumor the size of a golf ball that had begun to spread. Aggressive treatment seems to have left Billingsley cancer free. Now she's on a mission to persuade family and friends to be screened. "I just goad them until they do it," she says. Katie Couric would be proud...