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...original test-tube trials, reported last week in the Proceedings of the National Academy of Sciences, the drug appeared to prevent some, but not all, HIV-infected cells from producing any new copies of the virus. Thalidomide apparently accomplished this feat by inhibiting a naturally occurring substance called tumor necrosis factor (TNF). Its purpose in the body is to fight cancer and infections, and a side effect of its activity is severe weight loss. In people who are infected with HIV, for some unknown reason, TNF also promotes production of the virus. "We thought that if we could inhibit...

Author: /time Magazine | Title: An Old New Drug for AIDS | 7/12/1993 | See Source »

British scientists have managed to deactivate cancer cells in mice. They moved a gene from a bacterium into the tumor cells; once inside, the gene forced the cells to produce a toxic protein that then shut off the tumor cells' ability to reproduce and spread...

Author: /time Magazine | Title: Health Report: Jul. 5, 1993 | 7/5/1993 | See Source »

...When a young boy from Louisiana told Clinton that his 10-year-old brother died because of a brain tumor that may have been caused by pollution . . . Clinton's eyes seemed to redden with tears." -- HOUSTON CHRONICLE...

Author: /time Magazine | Title: Hands Have No Tears to Flow, but Presidents Do | 6/28/1993 | See Source »

While still in the testing stages, Friend hopes the technique, which measures the levels of the product of a genetic tumor suppressor known as p53, will decrease the amount of time necessary to screen patients from weeks to just hours...

Author: By Ivan Oransky, | Title: Elusive Genes Discovered | 6/10/1993 | See Source »

...sisters remember the eczema. "I'd wake up in the middle of the night and hear her scratching herself with a comb or brush," says Nan. "I don't think she ever slept the night through." When Sue was 12, a malignant tumor appeared on her forehead; doctors were able to remove it, but more than 10 operations were needed to rebuild her eyebrow and part of her eyelid. "I just remember, she always had a big bandage around her head," says Mary...

Author: /time Magazine | Title: Sisters Of Mercy | 5/31/1993 | See Source »

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