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Scientists have been exploring alternatives to the traditional—but harmful—retrovirus approach since researchers first reprogrammed human skin cells with the method late last year. Integrating these viruses into the cells' DNA causes permanent genetic manipulation, which can trigger malignant tumor growth, making them unsafe for human use. Scientists ultimately hope to clear this hurdle and treat a wide variety of human diseases by transplanting body tissues created from stem cells. Only three weeks ago, Harvard Medical School professor Konrad A. Hochedlinger and his colleagues at HSCI reported that they created mouse iPS cells using harmless...

Author: By June Q. Wu, CRIMSON STAFF WRITER | Title: Safer Stem Cells on Horizon, Harvard Researchers Say | 10/15/2008 | See Source »

...protein modeling computer program Pymol, or coming up with some harebrained scheme to entertain and distract his friends, they said. The aspiring oncologist passed away last week at the age of 19, bringing an end to his four-and-a-half year battle with desmoplastic small round cell tumor, a rare and aggressive form of cancer. Friends and family said that Friedman exuded brightness—both in his intellect and his personality. His optimism even in the face of his bleak prognosis was the first trait noted by all who spoke of him. “Mikey had this...

Author: By Aditi Balakrishna, CRIMSON STAFF WRITER | Title: Kirkland Student Dies of Cancer | 10/13/2008 | See Source »

...apply that to a brain tumor in a person? That’s the next step...

Author: By Alissa M D'gama, CRIMSON STAFF WRITER | Title: Researchers Shrink Brain Tumors in Mice | 10/10/2008 | See Source »

Another benefit of creating a “zone of resistance” is that when the gene is injected in one side of the brain, it can eliminate a tumor on the other, or contralateral, side, according to Anat O. Stemmer-Rachamimov, a pathologist at MGH and another of the study’s authors...

Author: By Alissa M D'gama, CRIMSON STAFF WRITER | Title: Researchers Shrink Brain Tumors in Mice | 10/10/2008 | See Source »

...researchers are now looking to test the therapy in brain tumors of dogs, which would prove beneficial for veterinarians, who currently can do little more than diagnose the tumor...

Author: By Alissa M D'gama, CRIMSON STAFF WRITER | Title: Researchers Shrink Brain Tumors in Mice | 10/10/2008 | See Source »

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